About Sildenafil Citrate and other drug interactions

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What is Viagra, also known as Sildenafil citrate, is one of the group of drugs called Phosphodiesterase type 5 (PDE-5) inhibitors. Viagra plus other PDE-5 inhibitors help men who have erectile dysfunction or male impotence by assisting in erectile response when he is sexually aroused or stimulated. Apart from Viagra, there are also other drugs classified under PDE-5 such as Cialis, also called Tadalafil and Levitra or Vardenafil. Viagra is only used by men. Women are not allowed to use it.

How does it work?

Viagra is not meant to arouse a man sexually but helps him effectively when he is sexually aroused. When a man is sexually stimulated, nitric oxide is released from penile tissues. Nitric oxide stimulates the production of cyclic guanosine monophosphate which relaxes the penis arteries thus allowing the blood to flow into the penis and then erectile tissues get filled with blood thus resulting to erection. The work of Viagra here is to maintain the level of cyclic guanosine monophosphate.

Is Viagra effective?

Medical studies and researches have proved that Viagra produces significant results in erectile function among the men as compared to other products such as placebo. It is also important to note that Viagra is note always good for every person thus you are asked to seek doctors advice before taking Viagra.
It is now proved that Viagra also slightly lowers the blood pressure of an individual. But it should not be used when taking nitrates. When you combine Viagra with nitrates, the result is that your blood pressure is lowered to a level that is fatal.

Work rate
Generally, Viagra is designed to produce results within a very short time, at most an hour. The Viagra tablet can be taken on an empty stomach and it can remain effective for up to six hours. When you take it after taking a fatty meal, the effects can be seen after a much longer time.
There are three dosages of Viagra; 100mg, 50mg and 25mg. Some men respond to lower dosage of Viagra while others may already be taking some other drugs that interact with Viagra thus there is need to change the dosage of Viagra.

Interaction with other drugs

Viagra interacts with a number of other drugs and therefore it is very crucial to inform your doctor about the drug you are currently taking, examples of other drugs that perform the same function include:
-Nitrate medications such as glyceryl trinitrate, isosorbide mononitrate, nitroglycerin or dinitrate
- Mibefradil
-Azole antifungal such as itraconazole and ketoconazole
-Rifamycins like rifampicin
-Alpha blockers which is prescribed for treatment of prostate disease and blood pressure
-Isopropyl or Butyl nitrates
You may not be able to see or feel the results of Viagra when you use it for the first time. It is advisable to take Viagra at least for eight times before opting for the second option if does not work.

The side effects

Viagra has side effects that are only mild and brief. Some of the most common side effects are facial flushing and headaches. Some users also experience stuffy nose, indigestion and a blue tint on the eyes.